Main Article Content
Antibacterial activity, Diabetic foot infection, Salix alba.
This study was planned to determine the frequency and in-vitro susceptibility pattern of aerobic bacterial isolates from diabetic foot infections against different antimicrobial agents. A total of 62 isolated bacteria comprising of 44 (71%) Gram-positive bacteria and 18 (29%) Gram-negative bacteria were isolated from 50 specimens and the majority of infections were predominantly due to 38(76%) mono-bacterial and 12 (24%) mixed-bacterial. All bacterial isolates were tested for their in-vitro susceptibility to antibiotics using disc diffusion technique and broth method [(MIC) minimum inhibitory concentration]. Anti-microbial susceptibility results showed that vancomycin showed activity against Gram-positive bacteria while both gentamycin and ciprofloxacin had overall anti-microbial activity against Pseudomonas aeruginosa and Escherichia coli. Whereas Serratia spp. susceptible to tested antibiotic except for streptomycin. Broth macrodilution susceptibility testing demonstrated that 35/62 (56.4% %) aerobic bacterial isolates exhibited a MIC of 1.5g/mL for leaf extract of Salix alba, and 62/62 (100%) were susceptible with a MIC of ≤ 3 g/mL.
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