Antimicrobial susceptibility profile of aerobic bacteria collected from diabetic foot ulcer infections, In Sulaimani Province

Main Article Content

Sirwan Muhsin Muhammed Ameen
Samira Mohammed Rasul

Keywords

Antibacterial activity, Diabetic foot infection, Salix alba.

Abstract

ABSTRACT


This study was planned to determine the frequency and in-vitro susceptibility pattern of aerobic bacterial isolates from diabetic foot infections against different antimicrobial agents. A total of 62 isolated bacteria comprising of 44 (71%) Gram-positive bacteria and 18 (29%)  Gram-negative bacteria were isolated from 50 specimens and the majority of infections were predominantly due to 38(76%) mono-bacterial and 12 (24%) mixed-bacterial. All bacterial isolates were tested for their in-vitro susceptibility to antibiotics using disc diffusion technique and broth method [(MIC) minimum inhibitory concentration]. Anti-microbial susceptibility results showed that vancomycin showed activity against Gram-positive bacteria while both gentamycin and ciprofloxacin had overall anti-microbial activity against Pseudomonas aeruginosa and Escherichia coli. Whereas Serratia spp. susceptible to tested antibiotic except for streptomycin. Broth macrodilution susceptibility testing demonstrated that 35/62 (56.4% %) aerobic bacterial isolates exhibited a MIC of 1.5g/mL for leaf extract of Salix alba, and 62/62 (100%) were susceptible with a MIC of ≤ 3 g/mL.

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