Synthesis and spectroscopic study of 1,2-thiazine system incorporating various ester groups

Abstract

       A series of 3-substituted-methyl-1,2-thiazines (4 a-g)  was exclusively obtained in high yields for the first time through nucleophilic substitution reaction of 4,6-dibromo-2- phenyl-5-methyl-3-bromomethyl-1,1-dioxo-1,2-thiazines (3) with each of sodium  Formate, acetate, propanoate, glycinate, benzoate, glycolate and salicylate as nucleophilic reagents in a highly polar aprotic solvent at room temperature.  The IR, 1H- and 13C-NMR and  MS spectra of the prepared compounds were conformed to their proposed structures
Published
Apr 18, 2018
How to Cite
. Synthesis and spectroscopic study of 1,2-thiazine system incorporating various ester groups. ZANCO Journal of Pure and Applied Sciences, [S.l.], v. 30, n. 1, p. 44-55, apr. 2018. ISSN 2412-3986. Available at: <http://zancojournals.su.edu.krd/index.php?journal=JPAS&page=article&op=view&path%5B%5D=1661>. Date accessed: 23 may 2018.
Section
Articles

Keywords

1, 2- thiazine, Carboxylate ion, Nucleophilic substitution, Ester