Antioxidant, and Antimicrobial Activities of Phenolic and Flavonoid Rich Medicinal Plants (Fritillaria zagrica and Tulipa kurdica) Bulbs Collected in Kurdistan Region of Iraq

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Mukhlis Hamad Aali
Nadhum J. Ismaiel
Fadzilah A. Abdul Majid


Fritillaria zagrica, Tulipa kurdica, Antioxidant, Antimicrobial Activity, TPC, TFC.


Fritillaria zagrica and Tulipa kurdica had been used as traditional herbal remedies since antiquity to treat human diseases in the Kurdistan region of Iraq. This is the first report and conceive to analyze these two medicinal plants based. Methanol, 80% ethanol and aqueous extracts of two medicinal plants (Fritillaria zagrcia and Tulipa kurdica) were evaluated for their antibacterial activity and antifungal activities. We have quantified the total phenolic (TPC) and flavonoid (TFC) contents and their relation to antioxidants (ABTS) [2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonate) and 2,2′-diphenyl-1 picryl hydrazyl (DPPH)scavenging free radicals in a dose dependent method. Results showed that F. zagrica and T. kurdica bulb extractions by using different solvents exhibited strong Antimicrobial activities against selected bacterial and fungal strains except C. guilliermondii ATCC 6260. Aqueous bulb extract of F. zagrica and T. kurdica showed better antibacterial activity compared to other solvent extracts. Methanol F. zagrica bulb extracts contain significantly higher phenolic content than T. kurdica. The TPC and TFC contents were varied between the plant bulb extracts and the DPPH and ABTS scavenging activities were exhibited to be significantly correlated with the amount of TPC and TFC.

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